Recent News & Events

  • HiTS Seminar: Keith Flaherty, MD, 10:00 am, Thursday, May 16, 2019 May 2, 2019 -   Keith Flaherty, M.D. Director of Clinical Research, Massachusetts General Hospital Professor of Medicine, Harvard Medical School   Determinants of response and resistance to targeted therapies and immunotherapy in melanoma   Significant therapeutic advances have been made in advanced melanoma over the past decade. For almost half of melanoma patients, BRAF inhibitor-based therapy has provided […]
  • HiTS Seminar: Christina Leslie, 10:00 am, Thursday, May 2, 2019 April 26, 2019 -   Christine Leslie, Ph.D. Associate Member, Computational Biology Program Sloan Kettering Institute   Decoding Epigenetic States of Immune and Cancer Cells   Dysregulated epigenetic programs are a feature of many cancers, and the diverse differentiation states of immune cells as well as their dysfunctional states in tumors are in part epigenetically encoded.  We will present […]
  • Using a Promiscuous Inhibitor to Uncover Cancer Drug Targets April 4, 2019 - American Society for Biochemistry and Molecular Biology Scientists at Harvard Medical School and the Dana-Farber Cancer Institute have developed a method that exploits the multitargeted nature of a chemical inhibitor to pinpoint vulnerabilities within cancer cells. When signaling pathways within cells are triggered, proteins activate through a chain reaction, like a row of tumbling dominoes, […]
  • HiTS Seminar: Matthew Vander Heiden, 10:00 am, Thursday, April 18, 2019 April 3, 2019 -   Matthew Vander Heiden, M.D., Ph.D. Associate Professor of Biology and Associate Director The Koch Institute of Integrative Cancer Research at MIT   Metabolic Constraints of Cell Proliferation   Complex regulatory mechanisms enable cell metabolism to match physiological state. The major pathways cells use to turn nutrients into energy and to synthesize macromolecules have been […]
  • HiTS Seminar: Elias Bareinboim, 10:00 am, Thursday, March 21, 2019 March 11, 2019 -   Elias Bareinboim, Ph.D. Purdue University   Causal Inference and Fusion   Causal inference is usually dichotomized into two categories, experimental (Fisher, Cox, Cochran) and observational (Neyman, Rubin, Robins, Dawid, Pearl) which, by and large, are studied separately. Understanding reality is more demanding. Experimental and observational studies are but two extremes of a rich spectrum […]