Recent News & Events

  • Using a Promiscuous Inhibitor to Uncover Cancer Drug Targets April 4, 2019- American Society for Biochemistry and Molecular Biology Scientists at Harvard Medical School and the Dana-Farber Cancer Institute have developed a method that exploits the multitargeted nature of a chemical inhibitor to pinpoint vulnerabilities within cancer cells. When signaling pathways within cells are triggered, proteins activate through a chain reaction, like a row of tumbling dominoes, […]
  • HiTS Seminar: Matthew Vander Heiden, 10:00 am, Thursday, April 18, 2019 April 3, 2019-   Matthew Vander Heiden, M.D., Ph.D. Associate Professor of Biology and Associate Director The Koch Institute of Integrative Cancer Research at MIT   Metabolic Constraints of Cell Proliferation   Complex regulatory mechanisms enable cell metabolism to match physiological state. The major pathways cells use to turn nutrients into energy and to synthesize macromolecules have been […]
  • HiTS Seminar: Elias Bareinboim, 10:00 am, Thursday, March 21, 2019 March 11, 2019-   Elias Bareinboim, Ph.D. Purdue University   Causal Inference and Fusion   Causal inference is usually dichotomized into two categories, experimental (Fisher, Cox, Cochran) and observational (Neyman, Rubin, Robins, Dawid, Pearl) which, by and large, are studied separately. Understanding reality is more demanding. Experimental and observational studies are but two extremes of a rich spectrum […]
  • HiTS Seminar: David Feldman, 10:00 am, Thursday, January 17, 2019 December 21, 2018-   David Feldman Broad Institute, Cambridge, MA   Scalable Image-based Genetic Screens   Genetic screens (e.g., CRISPR loss-of-function, ORF gain-of-function) provide a powerful means to identify genes underlying cellular processes. A wide range of cell behaviors can be observed by imaging assays, including dynamic responses from the scale of minutes to generations. However, image-based screens […]
  • HiTS Seminar: Luke Lee, PhD, 10:00 am, Tuesday, November 20, 2018 November 8, 2018-   Luke Lee, Ph.D. University of California, Berkeley   Ultrafast Photonic PCR and Organoids on Chip   10:00 am – 11:00 am Tuesday, November 20, 2018 Harvard Medical School 200 Longwood Avenue Warren Alpert Bldg, 5th Floor, Room 563 Boston, MA 02115 Hosted by Peter Sorger, Ph.D.