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We seek a talented, collaborative interdisciplinary scientist to catalyze the development and application of computational approaches for the analysis of high-dimensional cell and molecular profiling data and integrative modeling of multiscale dynamical biological systems. The successful candidate will work on computational analysis of large multi-omics datasets (including genomics, transcriptomics, proteomics, and phenomics) and mathematical modeling of complex biological systems. Expertise in predictive pattern recognition applied to molecular profiling data and mathematical modeling of biological and disease processes, and demonstrable ability to interpret the output of such analyses in the clinical context, are prerequisite. The successful candidate will be also expected to participate in collaborative projects with Seattle-based leading academic research groups on computational analysis of high-dimensional tissue, cell and molecular profiling data to advance Celgene’s patient-focused Molecular Medicine and Immuno-Oncology efforts.

Please apply here

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QSP-SB Industry & Academia Symposium

This symposium is a seminar series for presenting, learning, and discussing quantitative systems pharmacology (QSP) and systems biology (SB) topics. The goal of this event is to foster an active community of industry and academic participants interested in these topics, and create a forum for sharing our successes and challenges.

DATE: Tuesday February 9, 2016
TIME: 6:00 PM
LOCATION: Fred Rosen Conference Room Modell 100A
200 Longwood Ave, Boston, MA 02115

MIT Seminar Agenda


Hosted by

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HiTS Spring Symposium 2015

The HiTS Spring Symposium will take place on Friday, June 5, 2015 at the TMEC Amphitheater/Atrium.

Attendance at the Symposium will be comprised of LSP faculty, fellows, students and Therapeutics Graduate Program students. In addition to our community, we will be inviting our partners from MGH, DFCI, Biogen Idec, Merck, Novartis and other institutions. We look forward to an exciting day!

Download the Program/Abstract Book


10:00am – 10:30am Check In and Breakfast TMEC Atrium
10:30am – 12:30pm LSP Platforms and Capabilities TMEC Amphitheater
Antibody Resources Noel Peters, Liz Williams
Small Molecule Libraries and QC Caroline Shamu
LINCS Database Jeremy Muhlich, Liz Williams
Mass Spectometry and You Robert Everley
Imaging Tools and Applications Jagesh Shah
RNAseq Optimization and Use Mike Springer
12:30pm – 1:00pm BBQ Lunch TMEC Atrium
1:00pm – 2:20pm IDP Workshop TMEC Amphitheater
Laura Maliszewski, Galit Lahav, Catherine Dubreuil
2:20pm – 2:30pm Coffee Break TMEC Atrium
2:30pm – 3:30pm Therapeutics Seminar TMEC Amphitheater
Jeremy Duffield, Vice President of Research, Biogen Idec
3:30pm – 4:30pm HiTS Postdocs TMEC 250
Finding Fellowships Peter Sorger
3:30pm – 4:30pm Therapeutics Graduate Program Students TMEC Amphitheater
TGP Feedback Session David Golan, Catherine Dubreuil, EC Members
4:30pm – 6:30pm Poster Session TMEC Atrium
Reception and Awards
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Bioinformatician in Functional Genomics at Harvard Medical School

We are seeking a PhD-level bioinformatician with experience in functional genomics analysis and software development to provide informatics support for research projects using functional genomic and proteomic strategies (in particular CRISPR/Cas9, RNAi and mass spec) and to help establish and coordinate a new Bioinformatics Working Group at Harvard Medical School. The bioinformatician will (a) perform and/or train researchers to do gene-set enrichment, pathway analysis and network analyses of high-throughput functional genomics and proteomics datasets; (b) help with design of CRISPR short guide RNAs (sgRNAs) and CRISPR projects; (c) refine graphic user interfaces (GUIs) for existing online tools developed at HMS relating to functional genomics analysis, and co-develop new tools; (d) refine existing GUIs related to CRISPR-Cas9 technologies and co-develop new ones; and (e) establish regular meetings of the HMS Bioinformatics Working Group to foster communication, coordination and collaboration among the various groups that support bioinformatics at HMS, and to coordinate with bioinformatics resources at Harvard affiliate institutions.

Requirements: Ph.D in a life science field; previous experience in bioinformatics such as functional genomics data analysis; familiarity with public bioinformatics resources and tools; understanding of basic statistics; good understanding and practical experience in data management tools and applications; proficiency in a programming language such as Java, Perl or Python; excellent written and oral communication skills; strong organizational and interpersonal skills.

Applicants should send a cover letter and CV/resume to Stephanie Mohr, PhD, HMS Department of Genetics.  Email:

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The Harvard Therapeutics Graduate Program application is due on November 1st 2014. All G1 and G2 students from any HILS program are eligible.

Applicants will be interviewed in November and students will be notified of acceptance to the program in early December 2014.
For more information contact Dr. Catherine Dubreuil:

Download the Application here: Therapeutics Grad Program application 2014 Final

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