We work at the convergence of science, medicine, and engineering to reinvent the process of drug discovery and treatment.
The Harvard Program in Therapeutic Science (HiTS) is an academic research and education program that advances the fundamental science underlying human diseases and drug discovery in order to improve patient care.
The program’s faculty, trainees, and staff study disease using innovative approaches that fuse laboratory investigation, clinical research and computer science to accelerate the invention of life-saving medicines and the precision diagnostics needed to optimally treat individual patients. Our program brings together two approaches: Systems Pharmacology provides a powerful means to study the changes that promote disease and the ways in which therapeutic drugs function at a molecular level. Regulatory science focuses on the evaluation of drugs in clinical trials and on balancing the benefits and risks of new medicines.
Learn about our components:
Explore HiTS Research
News, Events, & Updates
Innovators in Therapeutics Speaker Series
Dr. David Altshuler, Executive VP, Global Research & CSO, Vertex Pharmaceuticals
March 24, 12:00pm ET
“New 3D Atlas of Colorectal Cancer Promises Improved Diagnosis, Treatment”
NIH Director’s Blog | January 31, 2023
2022 Global Conference on Regulatory Science Proceedings Available
Twitter @HiTSatHarvard
TODAY at 12:00 pm ET, @SantagataLab with the with the @harvardmed #HTAN will discuss using multiplexed tissue imaging to reveal the #SpatialBiology of cancer. https://www.cancer.gov/research/key-initiatives/moonshot-cancer-initiative/seminar-series #CMSSHTAN
We're delighted to announce that our paper on Biomappings has been published Oxford Bioinformatics. 🧵
https://doi.org/10.1093/bioinformatics/btad130
Multi-range ERK responses shape the proliferative trajectory of single cells following oncogene induction http://dlvr.it/Skwz3H
It's been a pleasure to work with @dexterpratt and the @NDExProject team on iQuery.
Interpreting gene sets w/ respect to causal, mechanistic networks can reveal more than simple terms.
Automated assembly of mechanisms with @indrasysbio enables scaling up network creation. https://twitter.com/IndraSysBio/status/1638177751256682501
🔬Do you have a list of genes from your latest experiment?
🌐You can paste them into iQuery on @NDExProject to calculate enrichment against biological networks from @news4go, @signor_database, @WikiPathways, and @theNCI-PID
iQuery is available at: https://www.ndexbio.org/iquery
Looking forward to speaking!! Will talk about the tools we are developing in the HTAN, insights from 2D & early 3D about the spatial features of cancer, steps toward clinical implementation combining H&E and IF, and high res 3D multiplexing for probing cell biology in tissues. https://twitter.com/NCIHTAN/status/1636752001961689089
Thursday, March 23 at 12:00 pm ET, @SantagataLab with the with the @harvardmed #HTAN will discuss the generation of pre-cancer atlases of cutaneous and hematologic origin. https://www.cancer.gov/research/key-initiatives/moonshot-cancer-initiative/seminar-series #CMSSHTAN