We work at the convergence of science, medicine, and engineering to reinvent the process of drug discovery and treatment.
The Harvard Program in Therapeutic Science (HiTS) is an academic research and education program that advances the fundamental science underlying human diseases and drug discovery in order to improve patient care.
Our faculty, trainees, and staff study disease using innovative approaches that fuse laboratory investigation, clinical research, and computer science to accelerate the invention of the life-saving medicines and precision diagnostics that are needed to optimally treat individual patients.
HiTS brings together two approaches:
The Laboratory of Systems Pharmacology makes it possible to study the changes that promote disease and the ways in which therapeutic drugs function at the molecular level.
The Center for Regulatory Science focuses on evaluating drugs in clinical trials and balancing the benefits and risks of new medicines.
Explore HiTS Research
News, Events, & Updates
HiTS Social Lunch
“NIH Data Management Plans”
Sarah Arena and Allison Maier
December 6, 12-1:30pm | ARM108
Regulatory Science Forum
“The Impact on Risk Evaluation and Mitigation Strategies (REMS) on Clinical Practice and Generic Drug Availability”
Dr. Ameet Sarpatwari, Assistant Director at the Program On Regulation, Therapeutics, and Law (PORTAL)
November 7, 12:00pm ET
Regulatory Science Forum
“An Inflection Point for High-Quality Diagnostic Tests in Oncology”
Dr. Brian Alexander, CEO of Foundation Medicine
September 12, 12:00pm ET
Twitter @HiTSatHarvard
Congrats to CRS Fellow @ryanpknox on their new piece in @JAMAHealthForum investigating the outcomes of the 340B Drug Pricing Program on the American #healthcaresystem.
@AmeetSarpatwari @akesselheim @wbfeldman
#drugpricing #340B
2D & 3D multiplexed subcellular profiling of nuclear instability in cancer https://www.biorxiv.org/content/10.1101/2023.11.07.566063v1: Our pre-print on nuclear envelope rupture in cancer - tools to map NE rupture and GBM cell state and lineage in tissues; + high-res 3D tissue imaging. Congrats Shannon Coy + Team.
🍂The more friends, the merrier!
This year, we'll all come together for the Longwood Postdoc Association's Friendsgiving dinner on November 17th from 5-8pm at the Hale building.🦃.
Bring your favorite dessert and compete in our scrumptious 'Best Dessert' contest!🍰🍁
📰 November News Announcement: https://mailchi.mp/harvard/rdm-news-1123
So much 🆓 data skills training this month!
1⃣ RDM Seminars: http://bit.ly/RDM-Seminars
2⃣ @TheDMPTool Workshop @HMSCountway
3⃣ Metadata Webinar with @dataverseorg
4⃣@HiTSatHarvard Data to Discovery Seminar
... and more! 🥧
Excited to share our new manuscript titled, "Quality Control for Single Cell Analysis of High-plex Tissue Profiles using CyLinter", out now on bioRxiv (https://doi.org/10.1101/2023.11.01.565120). Details on this open-source software program can be found at https://labsyspharm.github.io/cylinter/.